New Study Confirms: Semaglutide Leads to Sustained Weight Loss, Not Just Temporary Results

If you’ve ever worried, “I’ll just gain it all back,” after stopping weight loss medication, it’s time to take a closer look at the science.
For years, one of the most common criticisms of weight loss injections like Semaglutide has been that they only offer short-term results. But new research is proving otherwise. In fact, long-term clinical trials are showing that Semaglutide not only helps people lose weight—it helps them keep it off.
How Semaglutide Supports Long-Term Success
Semaglutide works by mimicking GLP-1, a natural hormone that regulates hunger and fullness. Unlike traditional diets that rely on willpower, this medication addresses the biological drivers of overeating. It helps reduce appetite, improve insulin sensitivity, and slow down stomach emptying, making it easier to feel satisfied with less food.
Recent multi-year studies have shown that patients maintained significant weight loss over the span of four years. Compared to placebo groups, those on Semaglutide consistently had greater and more sustained weight reduction without the need for extreme dieting.
Busting the Myth: “You’ll Gain It All Back”
Yes, some people do regain weight after stopping GLP-1 medications—but this typically happens when the medication is discontinued without continued lifestyle support. The key isn’t staying on the medication forever, it’s using the time on treatment to build new, healthier habits.
That’s where expert guidance makes all the difference.
Why Ahvina Delivers Better, More Sustainable Results
At Ahvina, we combine the proven power of Semaglutide with real, human-centered care:
• Doctor-prescribed treatment delivered discreetly to your door
• Ongoing support from licensed medical professionals
• Guidance to help you build better habits, so your results stick
We don’t believe in “quick fix” culture. We believe in equipping you with the tools, science, and support to make lasting change.
Get doctor-prescribed weight loss from the comfort of your home, start today!
Take the first step—see if you qualify in just 60 seconds.
Sources:
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The New England Journal of Medicine – “Once-Weekly Semaglutide in Adults with Overweight or Obesity”
https://www.nejm.org/doi/full/10.1056/NEJMoa2032183 -
Nature Medicine – “Long-term weight loss effects of Semaglutide in obesity without diabetes”
https://www.nature.com/articles/s41591-024-02996-7 -
Reuters – “...weight loss sustained for four years in trial, Novo Nordisk says”
https://www.reuters.com/business/healthcare-pharmaceuticals/wegovy-weight-loss-sustained-four-years-trial-novo-nordisk-says-2024-05-13 -
The Guardian – “People who stop weight loss drugs return to original weight within year, analysis finds”
https://www.theguardian.com/society/2025/may/14/people-who-stop-weight-loss-drugs-return-to-original-weight-within-year-analysis-finds